USC vs. GSU Football Prediction & Odds - Sept. 6

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The USC Trojans (1-0) and the Georgia Southern Eagles (0-1) square off at Los Angeles Memorial Coliseum on Saturday, September 6, 2025.

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USC vs. Georgia Southern Matchup Info

  • Game date: Saturday, September 6, 2025
  • Game time: 7:30 p.m. ET
  • Location: Los Angeles, California
  • Venue: Los Angeles Memorial Coliseum
  • TV channel: Fox Sports 1
  • Live Stream: Watch this game on Fubo (Regional restrictions may apply)

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USC vs. Georgia Southern Odds and Prediction

  • Spread favorite: Trojans (-28.5)
  • Moneyline: Trojans (-7692), Eagles (+1920)
  • Total: 61 points
  • Pick ATS: Georgia Southern (+28.5)
  • Pick OU: Over (61)
  • Prediction: USC 44, Georgia Southern 27

Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.

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USC vs. Georgia Southern Betting Records and Insights

  • USC has won one game against the spread this season.
  • Georgia Southern is winless against the spread this season (0-1-0).
  • The Trojans have been favored by 28.5 points or more once this season, and covered the spread.
  • So far this season, each USC game has gone over the point total.
  • Games featuring Georgia Southern have gone over the point total once this year.

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