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The Notre Dame Fighting Irish (3-1) hope to continue a three-game home win streak when they host the USC Trojans (3-1) on November 21, 2025.
Friday's matchup between the Trojans and the Fighting Irish features a close line of USC -1.5. A 143.5-point total is set for the game.
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USC vs. Notre Dame Odds and Game Info
- Game day: Friday, November 21, 2025
- Game time: 6 p.m. ET
- TV channel: ESPN
- Location: South Bend, Indiana
- Arena: Purcell Pavilion
- Live stream: Watch this game on Fubo (Regional restrictions may apply)
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USC vs. Notre Dame Odds and Prediction
- Spread favorite: USC (-1.5)
- Moneyline: USC (-110), Notre Dame (-110)
- Total: 143.5 points
Pick ATS:Notre Dame (+1.5)
- Pick OU: Under (143.5)
- Prediction: Notre Dame 73, USC 69
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USC vs. Notre Dame Comparison (2024-25 Stats)
| USC Rank | USC Stat | Notre Dame Stat | Notre Dame Rank | |
|---|---|---|---|---|
| 10th | 80.7 | Points Scored | 84.4 | 6th |
| 71st | 59.4 | Points Allowed | 61.9 | 114th |
| 22nd | 17.1 | Assists | 17.4 | 19th |
| 111th | 14.2 | Turnovers | 14.5 | 135th |
| 65th | 44.0% | Field Goal % | 48.5% | 6th |
| 10th | 35.9% | Field Goal % Allowed | 36.5% | 16th |
USC 2024-25 Key Players
- JuJu Watkins scored 23.9 points and distributed 3.4 assists per game last season.
- Kiki Iriafen grabbed 8.4 boards per game while also scoring 18.0 points a contest.
- Watkins knocked down shots from beyond the arc at a clip of 1.9 per contest a season ago.
- Watkins averaged 2.2 takeaways per game, while Rayah Marshall compiled 2.2 rejections per contest.
Notre Dame 2024-25 Key Players
- Hannah Hidalgo put up 23.8 points per game last season to go with 5.0 rebounds and 3.6 assists.
- Liatu King pulled down 10.4 rebounds per game, while Olivia Miles averaged 5.8 assists per contest.
- Miles knocked down 2.1 threes per game a season ago.
- Hidalgo and Kate Koval were defensive standouts last season, with Hidalgo averaging 3.7 steals per game and Koval collecting 1.7 blocks per contest.
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