George Kittle Week 16 Preview vs. the Colts

George Kittle will be up against the third-worst passing defense in the NFL when his San Francisco 49ers play the Indianapolis Colts in Week 16, on Monday at 8:15 p.m. ET.

Kittle has pulled down 45 passes on 54 targets for 484 yards and six TDs, averaging 53.8 yards per game.

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Kittle vs. the Colts

• Kittle vs the Colts (since 2021): 1 GP / 83 REC YPG / 1 REC TD
• Six players have racked up 100 or more receiving yards in a game against Indianapolis in the 2025 season.
• The Colts have surrendered a TD pass to 18 opposing players this year.
• No player has recorded more than one TD reception against Indianapolis on the season.
• The Colts surrender 247.6 passing yards per game, the NFL's 30th-ranked pass defense this season.
• The Colts' defense ranks eighth in the league by giving up 1.3 passing touchdowns per game to opponents (18 total passing TDs).

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Kittle Receiving Insights

• Kittle, in the receiving game, has gone over on his receiving yards prop in five of nine games this season.
• Kittle has been targeted on 54 of his team's 480 passing attempts this season (11.2% target share).
• He has been targeted 54 times, averaging 9.0 yards per target (23rd in NFL).
• Kittle has had a touchdown catch in five of nine games this year, and he found the end zone more than once on one of those occasions.
• He has scored six of his team's 37 offensive touchdowns this season (16.2%).
• Kittle (10 red zone targets) has been targeted 12.8% of the time in the red zone (78 total red zone pass attempts on the team).

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Kittle's Recent Performance