In the contest between the San Francisco 49ers and Chicago Bears on Sunday, Dec. 28 at 8:20 p.m. ET, our projection system expects the 49ers to emerge victorious. Seeking projections on the final score, spread, and point total, too? Find a full game projection below.
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49ers vs. Bears Game Info and TV Channel
- When: Sunday, December 28, 2025 at 8:20 p.m. ET
- Where: Levi's Stadium in Santa Clara, California
- TV: NBC/Peacock
- Live Stream: Watch this game on Fubo (Regional restrictions may apply)
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Listen to the game on 107.7 The Bone
49ers vs. Bears Odds and Betting Info
- Spread favorite: 49ers (-3)
- Moneyline: 49ers (-169), Bears (+143)
- Total: 52.5 points
49ers vs. Bears Prediction
- Pick ATS: 49ers (-3)
- Pick OU: Under (52.5)
Prediction:
49ers 30 - Bears 19
Prediction derived from a team strength comparison algorithm. Multiple factors such as strength of wins and scoring margin are used to make this projection.
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49ers vs. Bears Betting Insights
- The 49ers have covered 10 times in 15 games with a spread this season.
- The Bears have compiled a 10-5-0 record against the spread this season.
- San Francisco has been favored by 3 points or more seven times this season, and covered the spread in six of those games.
- Chicago has covered the spread twice this season (2-2 ATS) when playing as at least 3-point underdogs.
- A total of nine out of 15 49ers games this season have gone over the point total.
- So far this year, seven out of the Bears' 15 games with a set over/under have gone over the point total.
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